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黄金艳

副研究员,博士生导师

生物信息学课题组组长
Email: jinyan@shsmu.edu.cn

> 研究方向

目前研究重点为:(1)高通量测序数据分析方法建立;(2)肿瘤数据分析;(3)白血病分子机制研究。

> 学习经历

2001/9 - 2007/5,同济大学,生物信息学,博士
1997/9 - 2001/3,同济大学,生物化学,学士

> 工作简历

1. 2012/3 – 2014/6,哈佛大学,公共卫生学院,Research Fellow
2. 2009/10 – 2011/10,法国国家基因测序中心(CNG)和人类多态性研究中心(CEPH)
3. 2008/6 - 2008/9,北京大学,生物信息中心,访问学者
4. 2007/6 - 2009/10,同济大学,生命学院,讲师

> 国家级与省部级科研项目

1. 国家青年自然科学基金项目,30900838、调控诱导性多能干细胞形成的基因和信号网络研究、2010/01 - 2012/12、20万元、已结题、主持。
2. 国家面上自然科学基金项目,81570122、血液病的基因组转录组生物信息学分析方法建立与研究、2019/01 - 2019/12、60万元、主持。

> 荣誊

浦江人才计划, 2015年,生物信息学。

> 近期主要论文

1. Jinyan Huang, Jun Chen, Jorge Esparza, Jun Ding, James Elder, Goncalo R. Abecasis, Young-Ae Lee, Miriam F Moffatt, William O C Cookson, Liming Liang, eQTL mapping identify insertion and deletion specific eQTLs in mutipule tissues, Nature Communication (2015).
2. Zhang J#, Jinyan Huang#, Chen Y N, et al. Whole genome and transcriptome sequencing of matched primary and peritoneal metastatic gastric carcinoma, Scientific Reports, 2015, 共同第一作者).
3. Juan Wang, Xueqiu Lin, Su Wang, Chenfei Wang, Qixuan Wang, Xikun Duan, Peng Lu, Qian Wang, Chengyang Wang, X. Shirley Liu, Jinyan Huang*, PHF8 associating with NRSF at gene promoter regions genome-wide regulating genes expression, Scientific Reports (2014, 通讯作者).
4. Jinyan Huang, Chen J, Lathrop M, Liang L., A tool for RNA sequencing sample identity check, Bioinformatics (2013).
5. Jinyan Huang*, V Renault, J Sengenes, N Touleimat, S Michel, M Lathrop, J Tost, MeQA: A pipeline for MeDIP-seq data quality assessment and analysis, Bioinformatics (2011, 通讯作者)
6. Janine F. Felix, et.al, Jinyan Huang, et.al, Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index, Human Molecular Genetics (2016)
7. Felix R Day, et.al, Jinyan Huang, et.al, Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair, Nature Genetics (2015)
8. Yu X J, et al. Jinyan Huang, et al. Characterization of somatic mutations in air pollution-related lung cancer, Ebiomedicine (2015)
9. Wu, Shuai-Lai#; Fu, Xing#; Huang, Jinyan#; Jia, Ting-Ting; Zong, Feng-Yang; Mu, Shi-Rong; Zhu, Hong; Yan, Yong; Qiu, Shuwei; Wu, Qun; Yan, Wei; Peng, Ying; Chen, Juxiang; Hui, Jingyi, Genome-wide analysis of YB-1-RNA interactions reveals a novel role of YB-1 in miRNA processing in glioblastoma multiforme, Nucleic Acids Research (2015), 共同第一作者.
10. Peter K. Joshi, et.al, Jinyan Huang, et.al, Directional dominance on stature and cognition in diverse human populations, Nature (2015).
11. Kathryn L. Lunetta, et.al, Jinyan Huang, et.al, Rare coding variants and X-linked loci associated with age at menarche, Nature Communication (2015).
12. Huang Tao, Jinyan Huang, Qi Q, Li Y, Bray GA, Rood J, Sacks FM, Qi L, PCSK7 Genotype Modifies Effect of a Weight-Loss Diet on 2-Year Changes of Insulin Resistance: The POUNDS LOST Trial, Diabetes Care, (2015)
13. Mohlke, Karen L, et.al, Jinyan Huang, et.al, New genetic loci link adipose and insulin biology to body fat distribution, Nature (2015).
14. O'Neal WK, et.al, Jinyan Huang, et.al, Gene Expression in Transformed Lymphocytes Reveals Variation in Endomembrane and HLA Pathways Modifying Cystic Fibrosis Pulmonary Phenotypes, The American Journal of Human Genetics (AJHG) (2015)
15. Lu Jiang, et.al, Jinyan Huang, et.al, Sai-juan Chen, Exome sequencing identifies somatic mutations of DDX3X in natural killer/T-cell lymphoma, Nature Genetics (2015)
16. Joseph Vijai, et.al, Jinyan Huang, et.al, A genome-wide association study of marginal zone lymphoma shows association to the HLA region, Nature Communication (2015).
17. Van der Valk RJ, et.al, Jinyan Huang, et.al, A Novel Common Variant in DCST2 is associated with Length in Early Life and Height in Adulthood, Human Molecular Genetics (2014)
18. Meian He, et.al, Jinyan Huang, et.al, Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci, Human Molecular Genetics (2014)
19. Qi Q, et.al, Jinyan Huang, et.al, FTO genetic variants, dietary intake and body mass index: insights from 177 330 individuals, Human Molecular Genetics (2014)
20. Skibola CF, et.al, Jinyan Huang, et.al, Genome-wide association study identifies five susceptibility loci for follicular lymphoma outside the HLA region, The American Journal of Human Genetics (AJHG) (2014)
21. James R Cerhan, et.al, Jinyan Huang, et.al, Genome-wide association study identifies multiple susceptibility loci for diffuse large B-cell lymphoma, Nature Genetics (2014)
22. Locke AE, et.al, Jinyan Huang, et.al, Elizabeth K Speliotes, Genetic studies of body mass index yield new insights for obesity biology, Nature (2015).
23. Peng Chen, et.al, Jinyan Huang, et.al, Multiple Non-glycemic Genomic Loci Are Newly Associated with Blood Level of Glycated Hemoglobin in East Asians, Diabetes (2014)
24. Qibin Qi, Audrey Y. Chu, Jae H. Kang, Jinyan Huang, et.al, Fried food consumption and genetic predisposition to obesity, BMJ (2014)
25. Tao Huang, Jianqin Sunc, Yanqiu Chenc, Hua Xiec, Danfeng Xuc, Jinyan Huang, Duo Li, Genetic variants in desaturase gene, erythrocyte fatty acids, and risk of type 2 diabetes in Chinese Hans, Nutrition (2014)
26. Baoshan Ma*, Jinyan Huang*, Liming Liang, Real-time online engine for expression quantitative trait loci analyses, Database: The Journal of Biological Databases and Curation (2014), 共同第一作者.
27. Tao Huang, JingJing Ren, Jinyan Huang and Duo Li, Association of homocysteine with type 2 diabetes: a meta-analysis implementing Mendelian randomization approach, BMC Genomics (2013)
28. Qixuan Wang*, Jinyan Huang*, et. al, CR Cistrome: a ChIP-Seq database for chromatin regulators and histone modification linkages in human and mouse, Nucleic Acids Research (2013), 共同第一作者.
29. Jinyan Huang*, An ensemble learning approach for prediction of phosphorylation sites, Int. J. Bioinformatics Research and Applications, (2011, corresponding author)